Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Prothrombin' and Ligand = 'BDBM50241503'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prothrombin (Homo sapiens (Human))	BDBM50241503 (2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-1-Benzopy...) Show SMILES Oc1cc2oc(c(O)cc2c(=[OH+])c1)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C15H10O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-6,16-17,19-20H/p+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
University of Lodz Curated by ChEMBL					Assay Description Inhibition of human thrombin amidolytic activity using D-Phe-Pip-Arg-pNA as substrate preincubated for 10 mins followed by substrate addition measure...				Med Chem Res 23: 2324-2337 (2014) Article DOI: 10.1007/s00044-013-0829-4 BindingDB Entry DOI: 10.7270/Q2377B7W
					More data for this Ligand-Target Pair
Prothrombin (Homo sapiens (Human))	BDBM50241503 (2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-1-Benzopy...) Show SMILES Oc1cc2oc(c(O)cc2c(=[OH+])c1)-c1ccc(O)c(O)c1 Show InChI InChI=1S/C15H10O6/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7/h1-6,16-17,19-20H/p+1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a
University of Lodz Curated by ChEMBL					Assay Description Inhibition of human thrombin assessed as equilibrium dissociation constant at 50 to 1000 uM by BIAcore analysis				Med Chem Res 23: 2324-2337 (2014) Article DOI: 10.1007/s00044-013-0829-4 BindingDB Entry DOI: 10.7270/Q2377B7W
					More data for this Ligand-Target Pair