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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene c-JUN/protein c-fos' and Ligand = 'BDBM50090408'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene c-JUN/protein c-fos


(Homo sapiens (Human))
BDBM50090408
PNG
(4-(3-Methyl-2,5-dioxo-2,5-dihydro-pyrrol-1-ylamino...)
Show SMILES CCOC(=O)c1cnc(nc1NN1C(=O)C=C(C)C1=O)C(F)(F)F |t:16|
Show InChI InChI=1S/C13H11F3N4O4/c1-3-24-11(23)7-5-17-12(13(14,15)16)18-9(7)19-20-8(21)4-6(2)10(20)22/h4-5H,3H2,1-2H3,(H,17,18,19)
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 1.00E+3n/an/an/an/an/an/a



Signal Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of AP-1 (activator protein-1) mediated transcriptional activation in Jurkat T-cells


Bioorg Med Chem Lett 10: 1645-8 (2000)


BindingDB Entry DOI: 10.7270/Q2F190XH
More data for this
Ligand-Target Pair