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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM205261'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM205261
PNG
(US9249125, 13)
Show SMILES COc1ccc(cn1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4[nH]ncc4c3)n2)c2ccccc12)C(C)(C)C
Show InChI InChI=1S/C35H32N10O3/c1-35(2,3)29-18-30(45(44-29)23-10-14-31(47-4)37-20-23)41-34(46)40-27-12-13-28(25-8-6-5-7-24(25)27)48-32-15-16-36-33(42-32)39-22-9-11-26-21(17-22)19-38-43-26/h5-20H,1-4H3,(H,38,43)(H,36,39,42)(H2,40,41,46)
PDB
MMDB

KEGG

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PC cid
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US Patent
n/an/a 3n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...


US Patent US9249125 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72QG
More data for this
Ligand-Target Pair