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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM205290'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM205290
PNG
(US9249125, 43)
Show SMILES COc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3ccc4n(CCN5CCOCC5)ncc4c3)n2)c2ccccc12)C(C)(C)C
Show InChI InChI=1S/C42H44N10O4/c1-42(2,3)37-26-38(52(49-37)30-10-12-31(54-4)13-11-30)47-41(53)46-34-14-16-36(33-8-6-5-7-32(33)34)56-39-17-18-43-40(48-39)45-29-9-15-35-28(25-29)27-44-51(35)20-19-50-21-23-55-24-22-50/h5-18,25-27H,19-24H2,1-4H3,(H,43,45,48)(H2,46,47,53)
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MMDB

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US Patent
n/an/a 2n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...

US Patent US9249125 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72QG
More data for this
Ligand-Target Pair