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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM205297'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM205297
PNG
(US9249125, 50)
Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5CC(=O)Nc5c4)n3)c3ccccc23)n(n1)-c1cccc(OCCN2CCOCC2)c1
Show InChI InChI=1S/C42H43N9O5/c1-42(2,3)36-26-37(51(49-36)29-7-6-8-30(25-29)55-22-19-50-17-20-54-21-18-50)47-41(53)46-33-13-14-35(32-10-5-4-9-31(32)33)56-39-15-16-43-40(48-39)44-28-12-11-27-23-38(52)45-34(27)24-28/h4-16,24-26H,17-23H2,1-3H3,(H,45,52)(H,43,44,48)(H2,46,47,53)
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MMDB

KEGG

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PC cid
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US Patent
n/an/a<1n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...

US Patent US9249125 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72QG
More data for this
Ligand-Target Pair