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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM205305'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM205305
PNG
(US9249125, 58)
Show SMILES CN(C)CCOc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3cc(C)c4[nH]ncc4c3)c2)c2ccccc12)C(C)(C)C
Show InChI InChI=1S/C41H43N9O3/c1-26-21-28(22-27-25-43-47-39(26)27)44-37-23-31(17-18-42-37)53-35-16-15-34(32-9-7-8-10-33(32)35)45-40(51)46-38-24-36(41(2,3)4)48-50(38)29-11-13-30(14-12-29)52-20-19-49(5)6/h7-18,21-25H,19-20H2,1-6H3,(H,42,44)(H,43,47)(H2,45,46,51)
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MMDB

KEGG

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PC cid
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US Patent
n/an/a<1n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...

US Patent US9249125 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72QG
More data for this
Ligand-Target Pair