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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM205334'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM205334
PNG
(US9249125, 87)
Show SMILES Cc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4ccc(=O)n(CCO)c4)C(C)(C)C)c4ccccc34)n2)cc2cn[nH]c12
Show InChI InChI=1S/C37H36N10O4/c1-22-17-24(18-23-20-39-44-34(22)23)40-35-38-14-13-32(43-35)51-29-11-10-28(26-7-5-6-8-27(26)29)41-36(50)42-31-19-30(37(2,3)4)45-47(31)25-9-12-33(49)46(21-25)15-16-48/h5-14,17-21,48H,15-16H2,1-4H3,(H,39,44)(H,38,40,43)(H2,41,42,50)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...


US Patent US9249125 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72QG
More data for this
Ligand-Target Pair