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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM205335'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))
BDBM205335
PNG
(US9249125, 88)
Show SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc(Nc4ccc5[nH]ncc5c4)n3)c3ccccc23)n(n1)-c1ccc(=O)n(CCN2CCOCC2)c1
Show InChI InChI=1S/C40H41N11O4/c1-40(2,3)34-23-35(51(48-34)28-9-13-37(52)50(25-28)17-16-49-18-20-54-21-19-49)45-39(53)44-32-11-12-33(30-7-5-4-6-29(30)32)55-36-14-15-41-38(46-36)43-27-8-10-31-26(22-27)24-42-47-31/h4-15,22-25H,16-21H2,1-3H3,(H,42,47)(H,41,43,46)(H2,44,45,53)
PDB
MMDB

KEGG

UniProtKB/SwissProt

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DrugBank
antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 3n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...


US Patent US9249125 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72QG
More data for this
Ligand-Target Pair