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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM247085'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM247085
PNG
(3-((4-((4-(3-(3-(tert-butyl)-1-(p-tolyl)-1H-pyrazo...)
Show SMILES COc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(Oc2ccnc(Nc3cc(ccc3OC)C(=O)NCCN(C)C)n2)c2ccccc12)C(C)(C)C
Show InChI InChI=1S/C41H45N9O5/c1-41(2,3)35-25-36(50(48-35)27-13-15-28(53-6)16-14-27)46-40(52)45-31-17-19-33(30-11-9-8-10-29(30)31)55-37-20-21-43-39(47-37)44-32-24-26(12-18-34(32)54-7)38(51)42-22-23-49(4)5/h8-21,24-25H,22-23H2,1-7H3,(H,42,51)(H,43,44,47)(H2,45,46,52)
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US Patent
n/an/a<1n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...

US Patent US9701670 (2017)


BindingDB Entry DOI: 10.7270/Q2JM2CP2
More data for this
Ligand-Target Pair