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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM247105'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM247105
PNG
(3-((4-((4-(3-(3-cyclopropyl-1-(p-tolyl)-1H-pyrazol...)
Show SMILES COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4ccc(C)cc4)C4CC4)c4ccccc34)n2)cc(c1)C(=O)NCCN1CCOCC1
Show InChI InChI=1S/C42H43N9O5/c1-27-7-11-31(12-8-27)51-38(26-36(49-51)28-9-10-28)47-42(53)46-35-13-14-37(34-6-4-3-5-33(34)35)56-39-15-16-44-41(48-39)45-30-23-29(24-32(25-30)54-2)40(52)43-17-18-50-19-21-55-22-20-50/h3-8,11-16,23-26,28H,9-10,17-22H2,1-2H3,(H,43,52)(H,44,45,48)(H2,46,47,53)
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US Patent
n/an/a<1n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...

US Patent US9701670 (2017)


BindingDB Entry DOI: 10.7270/Q2JM2CP2
More data for this
Ligand-Target Pair