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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM247112'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Proto-oncogene tyrosine-protein kinase Src


(Homo sapiens (Human))		BDBM247112
PNG
(3-((4-((4-(3-(3-(tert-butyl)-1-(6-methoxypyridin-3...)
Show SMILES COc1cc(Nc2nccc(Oc3ccc(NC(=O)Nc4cc(nn4-c4ccc(OC)nc4)C(C)(C)C)c4ccccc34)n2)cc(c1)C(=O)NCCN1CCOCC1
Show InChI InChI=1S/C42H46N10O6/c1-42(2,3)35-25-36(52(50-35)29-10-13-37(56-5)45-26-29)48-41(54)47-33-11-12-34(32-9-7-6-8-31(32)33)58-38-14-15-44-40(49-38)46-28-22-27(23-30(24-28)55-4)39(53)43-16-17-51-18-20-57-21-19-51/h6-15,22-26H,16-21H2,1-5H3,(H,43,53)(H,44,46,49)(H2,47,48,54)
PDB
MMDB

KEGG

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PC cid
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US Patent
n/an/a<1n/an/an/an/an/an/a



RESPIVERT LIMITED; TOPIVERT PHARMA LIMITED

US Patent


Assay Description
The inhibitory activities of compounds of the invention against c-Src and Syk enzymes (Invitrogen), are evaluated in a similar fashion to that descri...

US Patent US9701670 (2017)


BindingDB Entry DOI: 10.7270/Q2JM2CP2
More data for this
Ligand-Target Pair