Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM4187'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM4187 (1,6-naphthyridin-2(1H)-one deriv. 7t | 3-(2,6-Dich...) Show SMILES CN1CCN(CCCOc2ccc(Nc3cc4n(C)c(=O)c(cc4cn3)-c3c(Cl)cccc3Cl)cc2)CC1 |(-18.38,8.29,;-17.09,7.44,;-15.72,8.14,;-14.43,7.29,;-14.52,5.75,;-13.19,4.98,;-13.19,3.44,;-11.85,2.67,;-11.85,1.13,;-10.52,.36,;-10.52,-1.18,;-9.18,-1.95,;-7.85,-1.18,;-6.52,-1.95,;-5.18,-1.18,;-3.85,-1.95,;-2.52,-1.12,;-1.18,-1.89,;-1.18,-3.43,;.15,-1.12,;1.48,-1.89,;.15,.42,;-1.18,1.19,;-2.52,.42,;-3.85,1.13,;-5.18,.36,;1.48,1.19,;1.48,2.73,;.15,3.5,;2.82,3.5,;4.15,2.73,;4.15,1.19,;2.82,.42,;2.82,-1.12,;-7.85,.36,;-9.18,1.13,;-15.9,5.06,;-17.18,5.91,)| Show InChI InChI=1S/C29H31Cl2N5O2/c1-34-12-14-36(15-13-34)11-4-16-38-22-9-7-21(8-10-22)33-27-18-26-20(19-32-27)17-23(29(37)35(26)2)28-24(30)5-3-6-25(28)31/h3,5-10,17-19H,4,11-16H2,1-2H3,(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland					Assay Description IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...				J Med Chem 43: 3134-47 (2000) Article DOI: 10.1021/jm000148t BindingDB Entry DOI: 10.7270/Q2028PQ1
					More data for this Ligand-Target Pair