BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM50088903'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Gallus gallus (Chicken))	BDBM50088903 (2-((4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Tested for inhibition of protein tyrosine kinase c-Src phosphorylation				Bioorg Med Chem Lett 10: 945-9 (2000) BindingDB Entry DOI: 10.7270/Q2R78DG4
Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50088903 (2-((4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	31.6	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Siena Curated by ChEMBL					Assay Description Inhibition of c-Src				Eur J Med Chem 44: 990-1000 (2009) Article DOI: 10.1016/j.ejmech.2008.07.002 BindingDB Entry DOI: 10.7270/Q2ZC8434
Universit£ degli Studi di Siena Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50088903 (2-((4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of c-Src kinase (unknown origin)				Citation and Details Article DOI: 10.1007/s00044-012-0308-3 BindingDB Entry DOI: 10.7270/Q2BZ68ZH
TBA					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50088903 (2-((4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description In vitro inhibition of Src protein tryrosine kinase using the Scintillation proximity kinase assay.				Bioorg Med Chem Lett 13: 3063-6 (2003) BindingDB Entry DOI: 10.7270/Q290235N
ARIAD Pharmaceuticals, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50088903 (2-((4-(4-amino-5-(3-methoxyphenyl)-7H-pyrrolo[2,3-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Pharma AG Curated by ChEMBL					Assay Description Tested for inhibition of protein tyrosine kinase c-Src phosphorylation in intact cells				Bioorg Med Chem Lett 10: 945-9 (2000) BindingDB Entry DOI: 10.7270/Q2R78DG4
Novartis Pharma AG Curated by ChEMBL					More data for this Ligand-Target Pair