BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM50303801'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50303801 (CHEMBL571546 \| N-benzyl-2-(5-(4-(2-morpholinoethox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	6.5	n/a	n/a	n/a	n/a	n/a	n/a
Athenex Inc. Curated by ChEMBL					Assay Description Inhibition of human c-SRC expressed in mouse NIH/3T3 cells assessed as inhibition of cell growth in presence of 0.5% FCS				J Med Chem 61: 4704-4719 (2018) Article DOI: 10.1021/acs.jmedchem.8b00164 BindingDB Entry DOI: 10.7270/Q2Z89GT1
Athenex Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50303801 (CHEMBL571546 \| N-benzyl-2-(5-(4-(2-morpholinoethox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Athenex Inc. Curated by ChEMBL					Assay Description Inhibition of human c-SRC expressed in mouse NIH/3T3 cells assessed as inhibition of cell growth in presence of 1.5% FCS by BrdU incorporation assay				J Med Chem 61: 4704-4719 (2018) Article DOI: 10.1021/acs.jmedchem.8b00164 BindingDB Entry DOI: 10.7270/Q2Z89GT1
Athenex Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50303801 (CHEMBL571546 \| N-benzyl-2-(5-(4-(2-morpholinoethox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier Curated by ChEMBL					Assay Description Inhibition of c-SRC				Bioorg Med Chem 19: 2517-28 (2011) Article DOI: 10.1016/j.bmc.2011.03.021 BindingDB Entry DOI: 10.7270/Q2DN45CD
Institut de Recherches Servier Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50303801 (CHEMBL571546 \| N-benzyl-2-(5-(4-(2-morpholinoethox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of src kinase				J Med Chem 53: 1238-49 (2010) Article DOI: 10.1021/jm901525b BindingDB Entry DOI: 10.7270/Q2QJ7J72
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50303801 (CHEMBL571546 \| N-benzyl-2-(5-(4-(2-morpholinoethox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of src kinase				J Med Chem 53: 1238-49 (2010) Article DOI: 10.1021/jm901525b BindingDB Entry DOI: 10.7270/Q2QJ7J72
Wyeth Research Curated by ChEMBL					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50303801 (CHEMBL571546 \| N-benzyl-2-(5-(4-(2-morpholinoethox...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Athenex Inc. Curated by ChEMBL					Assay Description Inhibition of Src (unknown origin)				J Med Chem 61: 4704-4719 (2018) Article DOI: 10.1021/acs.jmedchem.8b00164 BindingDB Entry DOI: 10.7270/Q2Z89GT1
Athenex Inc. Curated by ChEMBL					More data for this Ligand-Target Pair