Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Proto-oncogene tyrosine-protein kinase Src' and Ligand = 'BDBM6480'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM6480 (4-Anilino-7,8-dialkoxybenzo[g]quinoline-3-carbonit...) Show SMILES COc1cc2cc3c(Nc4ccc(Cl)cc4Cl)c(cnc3cc2cc1OCCN1CCOCC1)C#N Show InChI InChI=1S/C27H24Cl2N4O3/c1-34-25-12-17-10-21-24(11-18(17)13-26(25)36-9-6-33-4-7-35-8-5-33)31-16-19(15-30)27(21)32-23-3-2-20(28)14-22(23)29/h2-3,10-14,16H,4-9H2,1H3,(H,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	7.5	30
Wyeth Research					Assay Description Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...				Bioorg Med Chem Lett 12: 2989-92 (2002) Article DOI: 10.1016/s0960-894x(02)00577-2 BindingDB Entry DOI: 10.7270/Q24B2ZHC
					More data for this Ligand-Target Pair