Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Purine nucleoside phosphorylase (Rattus norvegicus) | BDBM50005799 (2,8-Diamino-9-benzyl-1,9-dihydro-purin-6-one | CHE...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP) | J Med Chem 37: 2477-80 (1994) BindingDB Entry DOI: 10.7270/Q21G0K9T | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purine nucleoside phosphorylase (Homo sapiens (Human)) | BDBM50005799 (2,8-Diamino-9-benzyl-1,9-dihydro-purin-6-one | CHE...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Tested for its inhibitory activity against human erythrocytic purine nucleoside phosphorylase | Bioorg Med Chem Lett 2: 407-410 (1992) Article DOI: 10.1016/S0960-894X(00)80157-2 BindingDB Entry DOI: 10.7270/Q2WD412N | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purine nucleoside phosphorylase (Homo sapiens (Human)) | BDBM50005799 (2,8-Diamino-9-benzyl-1,9-dihydro-purin-6-one | CHE...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
National Defense Medical Center Curated by ChEMBL | Assay Description PNP activity in human RBC | J Med Chem 36: 1024-31 (1993) BindingDB Entry DOI: 10.7270/Q2CV4JCQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purine nucleoside phosphorylase (Homo sapiens (Human)) | BDBM50005799 (2,8-Diamino-9-benzyl-1,9-dihydro-purin-6-one | CHE...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
Warner-Lambert Company Curated by ChEMBL | Assay Description Inhibitory activity against Purine nucleoside phosphorylase evaluated by radiochemical assay | J Med Chem 35: 1451-7 (1992) BindingDB Entry DOI: 10.7270/Q2MW2HSF | |||||||||||
More data for this Ligand-Target Pair |