Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Purine nucleoside phosphorylase' and Ligand = 'BDBM50293078'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50293078 (7-({[(2S,3R)-2,3,4-Trihydroxybutyl]amino}methyl)-3...) Show SMILES OC[C@@H](O)[C@@H](O)CNCc1c[nH]c2c1nc[nH]c2=O |r| Show InChI InChI=1S/C11H16N4O4/c16-4-8(18)7(17)3-12-1-6-2-13-10-9(6)14-5-15-11(10)19/h2,5,7-8,12-13,16-18H,1,3-4H2,(H,14,15,19)/t7-,8+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Industrial Research Limited Curated by ChEMBL					Assay Description Inhibition of human PNP by xanthine-oxidase coupled assay				J Med Chem 52: 1126-43 (2009) Article DOI: 10.1021/jm801421q BindingDB Entry DOI: 10.7270/Q2QR4Z18
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50293078 (7-({[(2S,3R)-2,3,4-Trihydroxybutyl]amino}methyl)-3...) Show SMILES OC[C@@H](O)[C@@H](O)CNCc1c[nH]c2c1nc[nH]c2=O |r| Show InChI InChI=1S/C11H16N4O4/c16-4-8(18)7(17)3-12-1-6-2-13-10-9(6)14-5-15-11(10)19/h2,5,7-8,12-13,16-18H,1,3-4H2,(H,14,15,19)/t7-,8+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Industrial Research Limited Curated by ChEMBL					Assay Description Inhibition of human PNP by xanthine-oxidase coupled assay				J Med Chem 52: 1126-43 (2009) Article DOI: 10.1021/jm801421q BindingDB Entry DOI: 10.7270/Q2QR4Z18
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Homo sapiens (Human))	BDBM50293078 (7-({[(2S,3R)-2,3,4-Trihydroxybutyl]amino}methyl)-3...) Show SMILES OC[C@@H](O)[C@@H](O)CNCc1c[nH]c2c1nc[nH]c2=O |r| Show InChI InChI=1S/C11H16N4O4/c16-4-8(18)7(17)3-12-1-6-2-13-10-9(6)14-5-15-11(10)19/h2,5,7-8,12-13,16-18H,1,3-4H2,(H,14,15,19)/t7-,8+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a	25
Industrial Research Limited; Albert Einstein College of Medicine of Yeshiva University US Patent					Assay Description The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...				US Patent US8853224 (2014) BindingDB Entry DOI: 10.7270/Q27H1H84
					More data for this Ligand-Target Pair
Purine nucleoside phosphorylase (Plasmodium falciparum)	BDBM50293078 (7-({[(2S,3R)-2,3,4-Trihydroxybutyl]amino}methyl)-3...) Show SMILES OC[C@@H](O)[C@@H](O)CNCc1c[nH]c2c1nc[nH]c2=O |r| Show InChI InChI=1S/C11H16N4O4/c16-4-8(18)7(17)3-12-1-6-2-13-10-9(6)14-5-15-11(10)19/h2,5,7-8,12-13,16-18H,1,3-4H2,(H,14,15,19)/t7-,8+/m0/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	25
Industrial Research Limited; Albert Einstein College of Medicine of Yeshiva University US Patent					Assay Description The inhibitor dissociation constants reported in Table 1 below are for phosphorolysis of inosine by PNP and were based on reaction rates measurements...				US Patent US8853224 (2014) BindingDB Entry DOI: 10.7270/Q27H1H84
					More data for this Ligand-Target Pair