Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Purine nucleoside phosphorylase (Homo sapiens (Human)) | BDBM50308522 (9-[7',7'-Difluoro-7'-(diethylphosphono)heptyl]-9-d...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Pharmacy and Life Sciences Curated by ChEMBL | Assay Description Inhibition of human erythrocyte PNP assessed as inhibition of 7-methylguanosine phosphorolysis after 50 mins by spectrophotometry in presence of 1 mM... | Bioorg Med Chem 18: 2275-84 (2010) Article DOI: 10.1016/j.bmc.2010.01.062 BindingDB Entry DOI: 10.7270/Q2N58MG0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purine nucleoside phosphorylase (Bos taurus (bovine)) | BDBM50308522 (9-[7',7'-Difluoro-7'-(diethylphosphono)heptyl]-9-d...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Pharmacy and Life Sciences Curated by ChEMBL | Assay Description Inhibition of calf spleen PNP assessed as inhibition of 7-methylguanosine phosphorolysis after 50 mins by spectrophotometry in presence of 1 mM inorg... | Bioorg Med Chem 18: 2275-84 (2010) Article DOI: 10.1016/j.bmc.2010.01.062 BindingDB Entry DOI: 10.7270/Q2N58MG0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purine nucleoside phosphorylase (Homo sapiens (Human)) | BDBM50308522 (9-[7',7'-Difluoro-7'-(diethylphosphono)heptyl]-9-d...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Pharmacy and Life Sciences Curated by ChEMBL | Assay Description Inhibition of human erythrocyte PNP assessed as inhibition of 25 uM 7-methylguanosine phosphorolysis by spectrophotometry in presence of 1 mM inorgan... | Bioorg Med Chem 18: 2275-84 (2010) Article DOI: 10.1016/j.bmc.2010.01.062 BindingDB Entry DOI: 10.7270/Q2N58MG0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Purine nucleoside phosphorylase (Bos taurus (bovine)) | BDBM50308522 (9-[7',7'-Difluoro-7'-(diethylphosphono)heptyl]-9-d...) | PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Tokyo University of Pharmacy and Life Sciences Curated by ChEMBL | Assay Description Inhibition of calf spleen PNP assessed as inhibition of 25 uM 7-methylguanosine phosphorolysis by spectrophotometry in presence of 1 mM inorganic pho... | Bioorg Med Chem 18: 2275-84 (2010) Article DOI: 10.1016/j.bmc.2010.01.062 BindingDB Entry DOI: 10.7270/Q2N58MG0 | |||||||||||
More data for this Ligand-Target Pair |