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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAC-alpha serine/threonine-protein kinase AKT1' and Ligand = 'BDBM50278533'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RAC-alpha serine/threonine-protein kinase AKT1


(Homo sapiens (Human))
BDBM50278533
PNG
(CHEMBL470192 | N-(2-amino-1-phenylethyl)-5-(1H-pyr...)
Show SMILES NCC(NC(=O)c1ccc(s1)-c1c[nH]c2ncccc12)c1ccccc1
Show InChI InChI=1S/C20H18N4OS/c21-11-16(13-5-2-1-3-6-13)24-20(25)18-9-8-17(26-18)15-12-23-19-14(15)7-4-10-22-19/h1-10,12,16H,11,21H2,(H,22,23)(H,24,25)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 16n/an/an/an/an/an/a



GlaxoSmithKline

Curated by ChEMBL


Assay Description
Inhibition of AKT1


Bioorg Med Chem Lett 19: 2244-8 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.094
BindingDB Entry DOI: 10.7270/Q24X57PX
More data for this
Ligand-Target Pair