Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM313615'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM313615 (N-(3-(6-ethoxy-5- (tetrahydro-2H-pyran-4- yl)pyrid...) Show SMILES CCOc1nnc(cc1C1CCOCC1)-c1cc(NC(=O)c2cc(cnn2)C(F)(F)F)ccc1C Show InChI InChI=1S/C24H24F3N5O3/c1-3-35-23-19(15-6-8-34-9-7-15)12-20(31-32-23)18-11-17(5-4-14(18)2)29-22(33)21-10-16(13-28-30-21)24(25,26)27/h4-5,10-13,15H,3,6-9H2,1-2H3,(H,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...				US Patent US10167279 (2019) BindingDB Entry DOI: 10.7270/Q2W0981V
					More data for this Ligand-Target Pair