Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM313635'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM313635 (4-chloro-N-(3-(2-(2- hydroxyethoxy)-6- (tetrahydro...) Show SMILES Cc1ccc(NC(=O)c2cc(Cl)ccn2)cc1-c1cc(OCCO)nc(c1)C1CCOCC1 Show InChI InChI=1S/C25H26ClN3O4/c1-16-2-3-20(28-25(31)23-14-19(26)4-7-27-23)15-21(16)18-12-22(17-5-9-32-10-6-17)29-24(13-18)33-11-8-30/h2-4,7,12-15,17,30H,5-6,8-11H2,1H3,(H,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...				US Patent US10167279 (2019) BindingDB Entry DOI: 10.7270/Q2W0981V
					More data for this Ligand-Target Pair