Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM313684'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM313684 ((R)-N-(3-(6-((1- hydroxypropan-2- yl)amino)-5-(tet...) Show SMILES C[C@H](CO)Nc1nnc(cc1C1CCOCC1)-c1cc(NC(=O)c2ccnc(c2)C(F)(F)F)ccc1C |r| Show InChI InChI=1S/C26H28F3N5O3/c1-15-3-4-19(32-25(36)18-5-8-30-23(11-18)26(27,28)29)12-20(15)22-13-21(17-6-9-37-10-7-17)24(34-33-22)31-16(2)14-35/h3-5,8,11-13,16-17,35H,6-7,9-10,14H2,1-2H3,(H,31,34)(H,32,36)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Assay Materials: Assay buffer is 50 mM Tris, pH 7.5, 15 mM MgCl2, 0.01% Bovine Serum Albumin (BSA) and 1 mM dithiothreitol (DTT); Stop buffer is 60 m...				US Patent US10167279 (2019) BindingDB Entry DOI: 10.7270/Q2W0981V
					More data for this Ligand-Target Pair