Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM50172063'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Mus musculus)	BDBM50172063 (CHEMBL3805849) Show SMILES Clc1ccc(cc1Cl)C1CC(=NN1c1ccccc1)c1ccc2OCCOc2c1 |c:11| Show InChI InChI=1S/C23H18Cl2N2O2/c24-18-8-6-16(12-19(18)25)21-14-20(26-27(21)17-4-2-1-3-5-17)15-7-9-22-23(13-15)29-11-10-28-22/h1-9,12-13,21H,10-11,14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
Nanjing University Curated by ChEMBL					Assay Description Inhibition of mouse c-Raf assessed as reduction in human full length N-terminal His-tagged MEK1 phosphorylation pre-incubated for 1 hr before MEK1 ad...				Bioorg Med Chem 24: 3052-3061 (2016) Article DOI: 10.1016/j.bmc.2016.05.012 BindingDB Entry DOI: 10.7270/Q2HX1FKZ
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