Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM50338874'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50338874 (CHEMBL1684784 | N-(5-Amino-1-(4-methoxybenzyl)-1H-...) Show SMILES COc1ccc(Cn2ncc(NC(=O)c3cc(NC(=O)c4cccc(c4)C(F)(F)F)ccc3C)c2N)cc1 Show InChI InChI=1S/C27H24F3N5O3/c1-16-6-9-20(33-25(36)18-4-3-5-19(12-18)27(28,29)30)13-22(16)26(37)34-23-14-32-35(24(23)31)15-17-7-10-21(38-2)11-8-17/h3-14H,15,31H2,1-2H3,(H,33,36)(H,34,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22.4	n/a	n/a	n/a	n/a	n/a	n/a
Hanyang University Curated by ChEMBL					Assay Description Inhibition of C-Raf assessed as [33P]gamma-ATP incorporation into substrate after 40 mins by scintillation counting				Bioorg Med Chem 19: 1915-23 (2011) Article DOI: 10.1016/j.bmc.2011.01.067 BindingDB Entry DOI: 10.7270/Q2D79CD3
					More data for this Ligand-Target Pair