Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM50340262'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50340262 (7-(2-(3-(2-methoxy-5-(trifluoromethyl)phenyl)ureid...) Show SMILES CNC(=O)c1cc2ccc(CCNC(=O)Nc3cc(ccc3OC)C(F)(F)F)cc2cn1 Show InChI InChI=1S/C22H21F3N4O3/c1-26-20(30)18-10-14-4-3-13(9-15(14)12-28-18)7-8-27-21(31)29-17-11-16(22(23,24)25)5-6-19(17)32-2/h3-6,9-12H,7-8H2,1-2H3,(H,26,30)(H2,27,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Curated by ChEMBL					Assay Description Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation counting				Bioorg Med Chem Lett 21: 2264-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.108 BindingDB Entry DOI: 10.7270/Q2MS3T23
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