Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM50340268'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50340268 (6-(2-(3-(2-methoxy-5-(trifluoromethyl)phenyl)ureid...) Show SMILES CNC(=O)c1nc2ccc(CCNC(=O)Nc3cc(ccc3OC)C(F)(F)F)cc2[nH]1 Show InChI InChI=1S/C20H20F3N5O3/c1-24-18(29)17-26-13-5-3-11(9-14(13)27-17)7-8-25-19(30)28-15-10-12(20(21,22)23)4-6-16(15)31-2/h3-6,9-10H,7-8H2,1-2H3,(H,24,29)(H,26,27)(H2,25,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Curated by ChEMBL					Assay Description Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation counting				Bioorg Med Chem Lett 21: 2264-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.108 BindingDB Entry DOI: 10.7270/Q2MS3T23
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