Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM50340271'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50340271 (6-(2-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido...) Show SMILES CNC(=O)c1nc2ccc(CCNC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)cc2[nH]1 Show InChI InChI=1S/C19H17ClF3N5O2/c1-24-17(29)16-27-14-5-2-10(8-15(14)28-16)6-7-25-18(30)26-11-3-4-13(20)12(9-11)19(21,22)23/h2-5,8-9H,6-7H2,1H3,(H,24,29)(H,27,28)(H2,25,26,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Curated by ChEMBL					Assay Description Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation counting				Bioorg Med Chem Lett 21: 2264-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.108 BindingDB Entry DOI: 10.7270/Q2MS3T23
					More data for this Ligand-Target Pair