Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM50340274'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50340274 (CHEMBL1760634 | N-(6-(2-(3-(3-(trifluoromethyl)phe...) Show SMILES CC(=O)Nc1nc2ccc(CCNC(=O)Nc3cccc(c3)C(F)(F)F)cc2[nH]1 Show InChI InChI=1S/C19H18F3N5O2/c1-11(28)24-17-26-15-6-5-12(9-16(15)27-17)7-8-23-18(29)25-14-4-2-3-13(10-14)19(20,21)22/h2-6,9-10H,7-8H2,1H3,(H2,23,25,29)(H2,24,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Curated by ChEMBL					Assay Description Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation counting				Bioorg Med Chem Lett 21: 2264-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.108 BindingDB Entry DOI: 10.7270/Q2MS3T23
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