Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM50340282'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50340282 (CHEMBL1760642 | N-(6-(2-(3-(4-chloro-2-(2-(methyla...) Show SMILES CNCCOc1cc(Cl)c(cc1NC(=O)NCCc1ccc2nc(NC(C)=O)[nH]c2c1)C(F)(F)F Show InChI InChI=1S/C22H24ClF3N6O3/c1-12(33)29-20-30-16-4-3-13(9-17(16)31-20)5-6-28-21(34)32-18-10-14(22(24,25)26)15(23)11-19(18)35-8-7-27-2/h3-4,9-11,27H,5-8H2,1-2H3,(H2,28,32,34)(H2,29,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Curated by ChEMBL					Assay Description Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation counting				Bioorg Med Chem Lett 21: 2264-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.108 BindingDB Entry DOI: 10.7270/Q2MS3T23
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