Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM50340284'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50340284 (CHEMBL1760735 | N-(6-(2-(3-(2-(2-aminoethoxy)-5-(t...) Show SMILES CC(=O)Nc1nc2ccc(CCNC(=O)Nc3cc(ccc3OCCN)C(F)(F)F)cc2[nH]1 Show InChI InChI=1S/C21H23F3N6O3/c1-12(31)27-19-28-15-4-2-13(10-16(15)29-19)6-8-26-20(32)30-17-11-14(21(22,23)24)3-5-18(17)33-9-7-25/h2-5,10-11H,6-9,25H2,1H3,(H2,26,30,32)(H2,27,28,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Curated by ChEMBL					Assay Description Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation counting				Bioorg Med Chem Lett 21: 2264-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.108 BindingDB Entry DOI: 10.7270/Q2MS3T23
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