Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM50340290'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50340290 (CHEMBL1760737 | N-(6-(2-(3-(2-(pyrrolidin-2-ylmeth...) Show SMILES CC(=O)Nc1nc2ccc(CCNC(=O)Nc3cc(ccc3OCC3CCCN3)C(F)(F)F)cc2[nH]1 Show InChI InChI=1S/C24H27F3N6O3/c1-14(34)30-22-31-18-6-4-15(11-19(18)32-22)8-10-29-23(35)33-20-12-16(24(25,26)27)5-7-21(20)36-13-17-3-2-9-28-17/h4-7,11-12,17,28H,2-3,8-10,13H2,1H3,(H2,29,33,35)(H2,30,31,32,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono Curated by ChEMBL					Assay Description Inhibition of human cRAF using [gamma-33P-ATP] as a substrate by scintillation counting				Bioorg Med Chem Lett 21: 2264-9 (2011) Article DOI: 10.1016/j.bmcl.2011.02.108 BindingDB Entry DOI: 10.7270/Q2MS3T23
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