Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RAF proto-oncogene serine/threonine-protein kinase' and Ligand = 'BDBM50358041'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
RAF proto-oncogene serine/threonine-protein kinase (Homo sapiens (Human))	BDBM50358041 (CHEMBL1917776) Show SMILES FC(F)(F)c1cc(ccc1Cl)C(=O)Nc1cccc(c1)C1=Nc2cnn(Cc3ccccc3)c2NC(=O)C1 |t:22| Show InChI InChI=1S/C27H19ClF3N5O2/c28-21-10-9-18(12-20(21)27(29,30)31)26(38)33-19-8-4-7-17(11-19)22-13-24(37)35-25-23(34-22)14-32-36(25)15-16-5-2-1-3-6-16/h1-12,14H,13,15H2,(H,33,38)(H,35,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	961	n/a	n/a	n/a	n/a	n/a	n/a
Hanyang University Curated by ChEMBL					Assay Description Inhibition of human CRAF using [gamma-33P]ATP after 40 mins by scintillation counting				Bioorg Med Chem 19: 6760-7 (2011) Article DOI: 10.1016/j.bmc.2011.09.042 BindingDB Entry DOI: 10.7270/Q2G44QPH
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