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Found 1 hit Enz. Inhib. hit(s) with Target = 'RNA-directed RNA polymerase (NS5B)' and Ligand = 'BDBM103255'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RNA-directed RNA polymerase (NS5B)


(Hepatitis C virus genotype 3a (isolate NZL1) (HCV))
BDBM103255
PNG
(US8546389, 22)
Show SMILES CCN(c1cc2nn(c(C(=O)NC)c2cc1C1CC1)-c1ccc(Nc2ccc(F)cc2)cc1)S(C)(=O)=O
Show InChI InChI=1S/C27H28FN5O3S/c1-4-32(37(3,35)36)25-16-24-23(15-22(25)17-5-6-17)26(27(34)29-2)33(31-24)21-13-11-20(12-14-21)30-19-9-7-18(28)8-10-19/h7-17,30H,4-6H2,1-3H3,(H,29,34)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 20n/an/an/an/an/an/a



Biota Scientific Management Pty Ltd.

US Patent


Assay Description
HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...


US Patent US8546389 (2013)

More data for this
Ligand-Target Pair