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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RNA-directed RNA polymerase (NS5B)' and Ligand = 'BDBM103266'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RNA-directed RNA polymerase (NS5B)


(Hepatitis C virus genotype 3a (isolate NZL1) (HCV))
BDBM103266
PNG
(US8546389, 166)
Show SMILES CNC(=O)c1n(nc2cc(N(CCCNC(=O)c3ccccc3)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1
Show InChI InChI=1S/C29H30BrN5O4S/c1-31-29(37)27-24-17-23(19-9-10-19)26(18-25(24)33-35(27)22-13-11-21(30)12-14-22)34(40(2,38)39)16-6-15-32-28(36)20-7-4-3-5-8-20/h3-5,7-8,11-14,17-19H,6,9-10,15-16H2,1-2H3,(H,31,37)(H,32,36)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 30n/an/an/an/an/an/a



Biota Scientific Management Pty Ltd.

US Patent


Assay Description
HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...


US Patent US8546389 (2013)


BindingDB Entry DOI: 10.7270/Q2DZ06XK
More data for this
Ligand-Target Pair