BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'RNA-directed RNA polymerase (NS5B)' and Ligand = 'BDBM103276'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
RNA-directed RNA polymerase (NS5B)


(Hepatitis C virus genotype 3a (isolate NZL1) (HCV))
BDBM103276
PNG
(US8546389, 191)
Show SMILES CNC(=O)c1n(nc2cc(N(CCCNC(=O)c3cccnc3)S(C)(=O)=O)c(cc12)C1CC1)-c1ccc(Br)cc1
Show InChI InChI=1S/C28H29BrN6O4S/c1-30-28(37)26-23-15-22(18-6-7-18)25(16-24(23)33-35(26)21-10-8-20(29)9-11-21)34(40(2,38)39)14-4-13-32-27(36)19-5-3-12-31-17-19/h3,5,8-12,15-18H,4,6-7,13-14H2,1-2H3,(H,30,37)(H,32,36)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 20n/an/an/an/an/an/a



Biota Scientific Management Pty Ltd.

US Patent


Assay Description
HCV polymerase inhibition assay: HCV polymerase reactions were carried out using a modified mothod of Howe et al., Antimicrobial Agents and Chemothe...


US Patent US8546389 (2013)

More data for this
Ligand-Target Pair