Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human)) | BDBM3032 (CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 143 | n/a | n/a | n/a | n/a | n/a | n/a |
Lawrence Berkeley National Laboratory Curated by ChEMBL | Assay Description Inhibition of human ErbB2 tyrosine kinase phosphorylation expressed in mouse BaF3 cells | J Med Chem 48: 7445-56 (2005) Article DOI: 10.1021/jm050607w BindingDB Entry DOI: 10.7270/Q26D5TT6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human)) | BDBM3032 (CHEMBL1204168 | CHEMBL29197 | N-(3-bromophenyl)-6,...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Napoli "Federico II" Curated by ChEMBL | Assay Description Inhibition of recombinant human HER2 expressed in insect cells using biotinyl-betaAbetaAbetaAAEEEEYFELVAKKK as substrate after 30 mins by HTRF method | Eur J Med Chem 150: 491-505 (2018) Article DOI: 10.1016/j.ejmech.2018.02.080 BindingDB Entry DOI: 10.7270/Q2B27XXB | |||||||||||
More data for this Ligand-Target Pair |