Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Receptor tyrosine-protein kinase erbB-2 (Homo sapiens (Human)) | BDBM50384888 (CHEMBL2035810) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 22.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Hanmi Research Center Curated by ChEMBL | Assay Description Inhibition of HER2 preincubated for 10 mins followed by incubation for 30 mins by fluorescence polarization assay | J Med Chem 55: 2846-57 (2012) Article DOI: 10.1021/jm201758g BindingDB Entry DOI: 10.7270/Q23T9J8F | |||||||||||
More data for this Ligand-Target Pair |