Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor-interacting serine/threonine-protein kinase 3' and Ligand = 'BDBM392810'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM392810 (N-(4-(1-(2-Fluoro-4-(trifluoromethyl)benzyl)-3-(4-...) Show SMILES Fc1ccc(cc1)-c1c2c(CCNC2=O)n(Cc2ccc(cc2F)C(F)(F)F)c1-c1ccnc(NC(=O)C2CC2)c1 Show InChI InChI=1S/C30H23F5N4O2/c31-21-7-4-16(5-8-21)25-26-23(10-12-37-29(26)41)39(15-19-3-6-20(14-22(19)32)30(33,34)35)27(25)18-9-11-36-24(13-18)38-28(40)17-1-2-17/h3-9,11,13-14,17H,1-2,10,12,15H2,(H,37,41)(H,36,38,40)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The assays were performed in black 1536-well plates. The final assay volume of 2 μl contained a mixture of a fluorescently labeled HTRF probe, T...				Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2M90C19
					More data for this Ligand-Target Pair