Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor-interacting serine/threonine-protein kinase 3' and Ligand = 'BDBM392840'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM392840 (US10301306, Example 38) Show SMILES COc1ccc(Cn2c3CCNC(=O)c3c(c2-c2ccncc2)-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C26H22FN3O2/c1-32-21-8-2-17(3-9-21)16-30-22-12-15-29-26(31)24(22)23(18-4-6-20(27)7-5-18)25(30)19-10-13-28-14-11-19/h2-11,13-14H,12,15-16H2,1H3,(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The assays were performed in black 1536-well plates. The final assay volume of 2 μl contained a mixture of a fluorescently labeled HTRF probe, T...				Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2M90C19
					More data for this Ligand-Target Pair