Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Receptor-interacting serine/threonine-protein kinase 3' and Ligand = 'BDBM392845'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Receptor-interacting serine/threonine-protein kinase 3 (Homo sapiens (Human))	BDBM392845 (US10301306, Example 43) Show SMILES Fc1ccc(cc1)-c1c2c(CCNC2=O)n(Cc2ccc(cc2F)C(F)(F)F)c1-c1ccncc1 Show InChI InChI=1S/C26H18F5N3O/c27-19-5-2-15(3-6-19)22-23-21(9-12-33-25(23)35)34(24(22)16-7-10-32-11-8-16)14-17-1-4-18(13-20(17)28)26(29,30)31/h1-8,10-11,13H,9,12,14H2,(H,33,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<30	n/a	n/a	n/a	n/a	n/a	n/a
GSK					Assay Description The assays were performed in black 1536-well plates. The final assay volume of 2 μl contained a mixture of a fluorescently labeled HTRF probe, T...				Bioorg Med Chem Lett 18: 5018-22 (2008) BindingDB Entry DOI: 10.7270/Q2M90C19
					More data for this Ligand-Target Pair