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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Regulator of G-protein signaling 8' and Ligand = 'BDBM50384740'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Regulator of G-protein signaling 8


(Homo sapiens (Human))
BDBM50384740
PNG
(CHEMBL2037231)
Show SMILES Fc1ccc(Cn2c(=O)sn(-c3cccc(c3)C(F)(F)F)c2=O)cc1
Show InChI InChI=1S/C16H10F4N2O2S/c17-12-6-4-10(5-7-12)9-21-14(23)22(25-15(21)24)13-3-1-2-11(8-13)16(18,19)20/h1-8H,9H2
PDB
MMDB

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PC cid
PC sid
UniChem
Article
n/an/a 1.62E+4n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of RGS8 interaction with Galpha0 protein by flow cytometry protein interaction assay


ACS Med Chem Lett 3: 146-150 (2012)


Article DOI: 10.1021/ml200263y
More data for this
Ligand-Target Pair