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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Regulator of G-protein signaling 8' and Ligand = 'BDBM50384741'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Regulator of G-protein signaling 8


(Homo sapiens (Human))
BDBM50384741
PNG
(CHEMBL2037232)
Show SMILES Cc1cccc(c1)-n1sc(=O)n(Cc2ccc(F)cc2)c1=O
Show InChI InChI=1S/C16H13FN2O2S/c1-11-3-2-4-14(9-11)19-15(20)18(16(21)22-19)10-12-5-7-13(17)8-6-12/h2-9H,10H2,1H3
PDB
MMDB

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PC cid
PC sid
UniChem
Article
n/an/a 7.10E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of RGS8 interaction with Galpha0 protein by flow cytometry protein interaction assay


ACS Med Chem Lett 3: 146-150 (2012)


Article DOI: 10.1021/ml200263y
More data for this
Ligand-Target Pair