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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Regulator of G-protein signaling 8' and Ligand = 'BDBM50384745'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Regulator of G-protein signaling 8


(Homo sapiens (Human))
BDBM50384745
PNG
(CHEMBL2037237)
Show SMILES Clc1ccc(cc1)-n1sc(=O)n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C15H11ClN2O2S/c16-12-6-8-13(9-7-12)18-14(19)17(15(20)21-18)10-11-4-2-1-3-5-11/h1-9H,10H2
PDB
MMDB

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CHEMBL
PC cid
PC sid
UniChem
Article
n/an/a 5.20E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of RGS8 interaction with Galpha0 protein by flow cytometry protein interaction assay


ACS Med Chem Lett 3: 146-150 (2012)


Article DOI: 10.1021/ml200263y
More data for this
Ligand-Target Pair