Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Renin (Homo sapiens (Human)) | BDBM50084627 ((R)-2-(2-Amino-thiazol-4-ylmethyl)-N*4*-cyclohexyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | 6.0 | n/a |
University of Queensland Curated by ChEMBL | Assay Description Inhibitory concentration against human plasma renin at pH 6. | J Med Chem 43: 305-41 (2000) Checked by Author BindingDB Entry DOI: 10.7270/Q2JD4XH4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Renin (Homo sapiens (Human)) | BDBM50084627 ((R)-2-(2-Amino-thiazol-4-ylmethyl)-N*4*-cyclohexyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | n/a | n/a | n/a | 0.000280 | 5.93 | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Curated by ChEMBL | Assay Description Component acylation rate constant by the compound against Renin was determined | J Med Chem 38: 1751-61 (1995) BindingDB Entry DOI: 10.7270/Q2K35SQR | |||||||||||
More data for this Ligand-Target Pair |