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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Renin' and Ligand = 'BDBM50144378'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Renin


(Rattus norvegicus)		BDBM50144378
PNG
(5-Chloro-1H-indole-2-carboxylic acid ((1S,2S,4S)-6...)
Show SMILES CNC(=O)[C@@H](C[C@H](O)[C@H](CC1CCCCC1)NC(=O)c1cc2cc(Cl)ccc2[nH]1)CC(Cl)=C
Show InChI InChI=1S/C25H33Cl2N3O3/c1-15(26)10-18(24(32)28-2)14-23(31)21(11-16-6-4-3-5-7-16)30-25(33)22-13-17-12-19(27)8-9-20(17)29-22/h8-9,12-13,16,18,21,23,29,31H,1,3-7,10-11,14H2,2H3,(H,28,32)(H,30,33)/t18-,21+,23+/m1/s1
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n/an/a 41n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibitory activity of compound against renin was determined

Bioorg Med Chem Lett 14: 2163-7 (2004)


Article DOI: 10.1016/j.bmcl.2004.02.020
BindingDB Entry DOI: 10.7270/Q2CV4H5M
More data for this
Ligand-Target Pair