Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Renin (Homo sapiens (Human)) | BDBM50325178 ((R)-3-amino-N-(2-chloro-5-(3-methoxypropyl)benzyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.0900 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Center for Therapeutic Research Curated by ChEMBL | Assay Description Inhibition of human recombinant renin in phosphate buffer | Bioorg Med Chem Lett 20: 5822-6 (2010) Article DOI: 10.1016/j.bmcl.2010.07.127 BindingDB Entry DOI: 10.7270/Q2ZP46BP | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Renin (Homo sapiens (Human)) | BDBM50325178 ((R)-3-amino-N-(2-chloro-5-(3-methoxypropyl)benzyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.0900 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibition of human recombinant renin in presence of pH 7.4 buffer | Bioorg Med Chem Lett 20: 5074-9 (2010) Article DOI: 10.1016/j.bmcl.2010.07.030 BindingDB Entry DOI: 10.7270/Q29P31V2 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Renin (Homo sapiens (Human)) | BDBM50325178 ((R)-3-amino-N-(2-chloro-5-(3-methoxypropyl)benzyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Inhibition of human recombinant renin in presence of plasma by immunoassay | Bioorg Med Chem Lett 20: 5074-9 (2010) Article DOI: 10.1016/j.bmcl.2010.07.030 BindingDB Entry DOI: 10.7270/Q29P31V2 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) | ||||||||||||
Renin (Homo sapiens (Human)) | BDBM50325178 ((R)-3-amino-N-(2-chloro-5-(3-methoxypropyl)benzyl)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Center for Therapeutic Research Curated by ChEMBL | Assay Description Inhibition of human recombinant renin in plasma | Bioorg Med Chem Lett 20: 5822-6 (2010) Article DOI: 10.1016/j.bmcl.2010.07.127 BindingDB Entry DOI: 10.7270/Q2ZP46BP | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) |