Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Renin' and Ligand = 'BDBM50340416'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Renin (Homo sapiens (Human))	BDBM50340416 (4-(3-(((3R,4S)-N-cyclopropyl-4-(4-(2-(2,6-dichloro...) Show SMILES COCCCc1cc(CN(C2CC2)C(=O)[C@H]2CNCC[C@@H]2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)cc(OCCC(C)(C)C(O)=O)c1 |r| Show InChI InChI=1S/C41H52Cl2N2O7/c1-27-20-36(42)38(37(43)21-27)52-19-18-51-32-11-7-30(8-12-32)34-13-15-44-25-35(34)39(46)45(31-9-10-31)26-29-22-28(6-5-16-49-4)23-33(24-29)50-17-14-41(2,3)40(47)48/h7-8,11-12,20-24,31,34-35,44H,5-6,9-10,13-19,25-26H2,1-4H3,(H,47,48)/t34-,35+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0200	n/a	n/a	n/a	n/a	7.4	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of human recombinant renin in PBS buffer using tetradecapeptide at pH 7.4				Bioorg Med Chem Lett 21: 2430-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.067 BindingDB Entry DOI: 10.7270/Q2G16157
					More data for this Ligand-Target Pair
Renin (Homo sapiens (Human))	BDBM50340416 (4-(3-(((3R,4S)-N-cyclopropyl-4-(4-(2-(2,6-dichloro...) Show SMILES COCCCc1cc(CN(C2CC2)C(=O)[C@H]2CNCC[C@@H]2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)cc(OCCC(C)(C)C(O)=O)c1 |r| Show InChI InChI=1S/C41H52Cl2N2O7/c1-27-20-36(42)38(37(43)21-27)52-19-18-51-32-11-7-30(8-12-32)34-13-15-44-25-35(34)39(46)45(31-9-10-31)26-29-22-28(6-5-16-49-4)23-33(24-29)50-17-14-41(2,3)40(47)48/h7-8,11-12,20-24,31,34-35,44H,5-6,9-10,13-19,25-26H2,1-4H3,(H,47,48)/t34-,35+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of human recombinant renin in human citrated-plasma				Bioorg Med Chem Lett 21: 2430-6 (2011) Article DOI: 10.1016/j.bmcl.2011.02.067 BindingDB Entry DOI: 10.7270/Q2G16157
					More data for this Ligand-Target Pair