Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Replication protein A 70 kDa DNA-binding subunit' and Ligand = 'BDBM260648'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replication protein A 70 kDa DNA-binding subunit (Homo sapiens (Human))	BDBM260648 (US9533969, TDRL-521) Show SMILES COc1ccc(cc1)C1=NN(C(C1)c1cn(nc1-c1ccc(C)cc1)-c1ccccc1)C(=O)CCC(O)=O |t:9| Show InChI InChI=1S/C30H28N4O4/c1-20-8-10-22(11-9-20)30-25(19-33(32-30)23-6-4-3-5-7-23)27-18-26(21-12-14-24(38-2)15-13-21)31-34(27)28(35)16-17-29(36)37/h3-15,19,27H,16-18H2,1-2H3,(H,36,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.17E+4	n/a	n/a	n/a	n/a	n/a	n/a
Indiana University Research and Technology Corporation US Patent					Assay Description Small molecule inhibitors were obtained from ChemDiv and resuspended in DMSO. Compound TDLR-505 was independently synthesized and structure confirmed...				US Patent US9533969 (2017) BindingDB Entry DOI: 10.7270/Q2445KDJ
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