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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Replicative DNA helicase' and Ligand = 'BDBM50179007'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Replicative DNA helicase


(Pseudomonas aeruginosa)		BDBM50179007
PNG
(6-(4-benzylpiperazin-1-yl)-N2,N4-bis(3,4-difluorop...)
Show SMILES Fc1ccc(Nc2nc(Nc3ccc(F)c(F)c3)nc(n2)N2CCN(Cc3ccccc3)CC2)cc1F
Show InChI InChI=1S/C26H23F4N7/c27-20-8-6-18(14-22(20)29)31-24-33-25(32-19-7-9-21(28)23(30)15-19)35-26(34-24)37-12-10-36(11-13-37)16-17-4-2-1-3-5-17/h1-9,14-15H,10-13,16H2,(H2,31,32,33,34,35)
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.00E+3n/an/an/an/an/an/a



Targanta Therapeutics Inc.

Curated by ChEMBL


Assay Description
Inhibition of Pseudomonas aeruginosa DnaB helicase

Bioorg Med Chem Lett 16: 1286-90 (2006)


Article DOI: 10.1016/j.bmcl.2005.11.076
BindingDB Entry DOI: 10.7270/Q2PG1R95
More data for this
Ligand-Target Pair