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Found 1 hit Enz. Inhib. hit(s) with Target = 'Replicative DNA helicase' and Ligand = 'BDBM50400421'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Replicative DNA helicase


(Bacillus anthracis)		BDBM50400421
PNG
(CHEMBL2178451)
Show SMILES CC(=O)NCCNC(=O)CCc1c(C)c2ccc(OCc3ccc(cc3)-c3ccccc3)c(C)c2oc1=O
Show InChI InChI=1S/C31H32N2O5/c1-20-26-13-15-28(37-19-23-9-11-25(12-10-23)24-7-5-4-6-8-24)21(2)30(26)38-31(36)27(20)14-16-29(35)33-18-17-32-22(3)34/h4-13,15H,14,16-19H2,1-3H3,(H,32,34)(H,33,35)
KEGG

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



Microbiotix Inc.

Curated by ChEMBL


Assay Description
Inhibition of Bacillus anthracis Sterne 34F2 replicative DNA helicase-mediated ATP-dependent dissociation of Hel-5'FAM:Hel-3'BHQ by FRET assay

J Med Chem 55: 10896-908 (2012)


Article DOI: 10.1021/jm300922h
BindingDB Entry DOI: 10.7270/Q2MS3TWV
More data for this
Ligand-Target Pair